Seeking Participants for Orthoses Trials
Researchers at Cerebral Palsy Alliance are conducting multicentre randomised controlled trials of rigid wrist/hand orthoses (splints) for children with cerebral palsy.
What is the purpose of the studies?
Occupational therapists use wrist/hand orthoses because we think they work however, we don’t have any real evidence of effectiveness, who they might be more useful for or how long they should be worn to achieve an effect. This study will provide important information regarding the long-term effects of upper limb orthoses in children with cerebral palsy.
How does the trial work?
Eligible and consenting children will be randomised to either wear a wrist/hand orthosis or to wear no orthosis at night and be monitored carefully for 3 years.
Who is eligible to participate?
There are two studies – one for younger children and the other for older children:
iWHOT trial – aims to prevent loss of movement and muscle stiffness and therefore, optimise hand function. It is for children:
- under 3 years of age with, or at risk of, cerebral palsy (unilateral or bilateral)
- with full wrist extension with fingers extended BUT abnormal posturing during rest or activity.
MITrial – aims to minimise impairment and is for children:
- aged 5 to 15 years
- with a score of at least 1 on the Modified Ashworth Scale of the wrist/hand flexors measured with fingers extended, that is, with some resistance detected throughout the range.
For more information about the Orthoses Study or to refer potential study participants, please contact Cerebral Palsy Alliance researcher Margaret Wallen.